Research in the Kopeček/Yang Biomedical Polymers Laboratory in the Center for Controlled Chemical Delivery focuses on the design, synthesis, and characterization of biomedical materials and macromolecular therapeutics. We are studying tailor-made hybrid macromolecules which mimic structures developed by Mother Nature. The interdisciplinary research field involves synthetic and physical chemistry, molecular engineering, pharmaceutics, molecular biology, and immunology. The major projects are described below:
- Evolution from Drug-Free Macromolecular Therapeutics (DFMT) to Multi-Antigen T Cell Hybridizers (MATCH)
- New Constructs of Antibody-Drug Conjugates (pADCs)
- Macromolecular Therapeutics
- Brain Delivery of Macromolecular Therapeutics