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May 9, 2025
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Kopecek / Yang Lab – University of Utah

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Department of Pharmaceutics and Pharmaceutical Chemistry

Department of Biomedical Engineering

Huntsman Cancer Institue

Biological Chemistry Program

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Recent Publications
    • Combination of Multivalent DR5 Receptor Clustering Agonists and Histone Deacetylase Inhibitors for Treatment of Colon Cancer. J. Li, J. Arnold, M. Sima, H. Al Faruque, J. Galang, S. Hu-Lieskovan, J. Kopeček, J. Yang. J. Controlled Release 376, 1014-1024 (2024) [doi]
    • Multiantigen T-Cell Hybridizers: A Two-Component T-Cell-Activating Therapy. M.T. Gambles, S. Li, I. Kendell, J. Li, D. Sborov, P. Shami, J. Yang, J. Kopeček. ACS Nano (2024) [doi]
    • Human Serum Albumin-Based Drug-Free Macromolecular Therapeutics Induce Apoptosis in Chronic Lymphocytic Leukemia Patient Cells by Crosslinking of CD20 and/or CD38 Receptors. J. Li, M.T. Gambles, B. Jones, J.A. Williams, N.J. Camp, P.J. Shami, J. Yang, J. Kopeček. Drug Delivery Translational Res. (2024); [doi].
    • Hydrophilic Biomaterials: From Crosslinked and Self-Assembled Hydrogels to Polymer-Drug Conjugates and Drug-Free Macromolecular Therapeutics. J. Kopeček. Invited “Magnum Opus” manuscript. J. Controlled Release 373, 1-22 (2024); [doi].
    • Obinutuzumab-Based Drug-Free Macromolecular Therapeutics Synergizes with Topoisomerase Inhibitors. M.T. Gambles, D. Sborov, P. Shami, J. Yang, J. Kopeček. Macromol. Biosci. (2023) 2300375; doi
    • Multi-Targeted Immunotherapeutics to Treat B Cell Malignancies. M.T. Gambles, J. Yang, J. Kopeček. J. Controlled Release 358, 232-258 (2023); doi
    • Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model. Z.-H. Peng, C.M. Jogdeo, J. Li, Y. Xie, Y. Wang, Y.M. Sheinin, J. Kopeček, D. Oupický. Pharmaceutics 14, 1725 (2022); doi

 

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