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March 7, 2026
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Kopecek / Yang Lab – University of Utah

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Department of Molecular Pharmaceutics

Department of Biomedical Engineering

Huntsman Cancer Institue

Biological Chemistry Program

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Recent Publications
    • Polymer-based Chemo-Immunotherapy Combining Immunogenic Cell Death Induction and PD-L1 Blockade Enhances Antitumor Immunity in Melanoma. J. Li, H. Al Faruque, E. Cortes-Sanchez, M. VanBrocklin, S. Hu-Lieskovan, M. Cina, A. Young, J. Kopeček, J. Yang, J. Controlled Release 114193 (2025) [doi]
    • Self-Assembling Multi-Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma. S. Li, J. Li, H.A. Faruque, P. Shami, B. Knoechel, J. Lohr, D. Sborov, J. Yang, J. Kopeček. Adv. Healthcare Mat. e02156 (2025) [doi]
    • CD38-targeted antibody-polymer drug conjugates for enhanced treatment of multiple myeloma. J. Li, S. Li, H.A. Faruque, J. Kopeček, D. Sborov, J. Yang. Biomaterials, 324, 123464 (2026) [doi]
    • Two-component T-cell immunotherapy enables antigen pre-targeting to reduce cytokine release without forfeiting efficacy. M.T. Gambles, I. Kendell, J. Li, K. Spaihower, D. Sborov, S. Owen, A. Stark, D. Bearss, J. Yang, J. Kopeček. Nanomedicine: Nanotechnology, Biology and Medicine 67, 102825 (2025) [doi]
    • PD-L1 targeted antibody-polymer-Epirubicin conjugate prolongs survival in a preclinical murine model of advanced ovarian cancer. J. Li, H.A. Al Faruque, S. Li, M. Sima, D. Sborov, S. Hu-Lieskovan, T. Werner, J. Kopeček, J. Yang. J. Controlled Release 382, 113682 (2025) [doi]

 

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